IGF 1LR3 1mg

IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1) is a synthetic, elongated analog of human IGF-1, engineered with an 83-amino acid sequence that includes a 13-amino acid extension at the N-terminus and an arginine substitution at position 3. These modifications dramatically reduce its binding affinity to IGF-binding proteins (IGFBPs), resulting in a significantly extended half-life compared to native IGF-1 — from minutes to several hours — and enhanced systemic bioavailability. As a potent activator of the IGF-1 receptor (IGF-1R), it stimulates downstream PI3K/Akt and MAPK/ERK signaling pathways, which are central to cellular proliferation, differentiation, and survival. IGF-1 LR3 is extensively studied in muscle biology, metabolic research, and regenerative science for its ability to promote anabolic signaling across multiple tissue types. For research purposes only.